April 25, 2022European Heart Journal39 citations

Timing of cardiac surgery during pregnancy: a patient-level meta-analysis

GSGijs J. van SteenbergenRadboud University Nijmegen QTQueeny H.Y. TsangRadboud University Nijmegen OHOlivier W.H. van der HeijdenRadboud University Nijmegen

Structured PICO

Does performing a cesarean section prior to cardiac surgery or the trimester of surgery affect maternal and foetal mortality in pregnant women?

Population

Pregnant women undergoing cardiac surgery

Intervention

Cesarean section (CS) prior to cardiac surgery and timing of surgery by trimester

Comparator

Cardiac surgery without prior CS and different trimesters of pregnancy

Outcome

Maternal mortality and foetal mortalityhard clinical

In pregnant women requiring cardiac surgery, maternal mortality is independent of the trimester, while foetal mortality is significantly reduced if a cesarean section is performed prior to the surgery when the fetus is viable.

Abstract

Maternal mortality after cardiac surgery during pregnancy is not associated with the trimester of pregnancy. Cardiac surgery is associated with high foetal mortality but is significantly lower in women where CS is performed prior to cardiac surgery. When the foetus is viable, CS prior to cardiac surgery might be safe. When CS is not feasible, trimester stage does not seem to influence foetal mortality.

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