Why the study?
Does vigorous physical activity impair myocardial function in patients with ARVC and mutation-positive family members?
Does vigorous physical activity impair myocardial function in patients with ARVC and mutation-positive family members?
Vigorous physical activity is associated with impaired biventricular function in ARVC patients and mutation-positive family members, suggesting exercise may accelerate myocardial dysfunction.
Exercise associated with impaired biventricular function in ARVC; hypothesis-generating and requires prospective trials before guiding activity restrictions.
Athletes showed reduced biventricular function compared with non-athletes in ARVC patients and in mutation-positive family members. The amount and intensity of exercise activity was associated with impaired LV and RV function. Exercise may aggravate and accelerate myocardial dysfunction in ARVC.
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Saberniak et al. (2014) studied this question.
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