Why the study?
Does TAVR with a self-expanding prosthesis improve survival at 1 year compared to surgical aortic-valve replacement in patients with severe aortic stenosis at increased surgical risk?
Does TAVR with a self-expanding prosthesis improve survival at 1 year compared to surgical aortic-valve replacement in patients with severe aortic stenosis at increased surgical risk?
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In high-risk patients with severe aortic stenosis, TAVR with a self-expanding prosthesis significantly improves 1-year survival compared to surgical aortic-valve replacement.
In patients with severe aortic stenosis who are at increased surgical risk, TAVR with a self-expanding transcatheter aortic-valve bioprosthesis was associated with a significantly higher rate of survival at 1 year than surgical aortic-valve replacement. (Funded by Medtronic; U.S. CoreValve High Risk Study ClinicalTrials.gov number, NCT01240902.).
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Adams et al. (2014) studied this question.
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