Comparison of invasive and non-invasive gradients before and after TAVI and their implications on clinical outcomes

Figures

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  Fig. 1. Discordance between non-invasive and invasive MGs pre- and post-TAVI (p < 0.001) as well as from pre to post-TAVI (p < 0.001). Data are presented as median and interquartile range. MG mean gradient, TAVI transcatheter aortic valve implantation; ***p < 0.001

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  Fig. 2. a Pearson correlation of concomitant invasive versus non-invasive MGs pre-TAVI (A) and post-TAVI (B). MG mean gradient, TAVI transcatheter aortic valve implantation. b Pearson correlation of concomitant invasive versus non-invasive MGs self- and balloon expandable valves, as well as corresponding distribution of absolute discrepancy of MGs pre-TAVI (A) and post-TAVI (B). MG mean gradient, TAVI transcatheter aortic valve implantation. c Pearson correlation of concomitant invasive versus non-invasive MGs for tertiles with small, medium and large SOVd, as well as corresponding distribution of absolute discrepancy of MGs pre-TAVI (A) and post-TAVI (B). MG mean gradient, SOVd sinus of valvalva diameter, TAVI transcatheter aortic valve implantation

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  Fig. 3. The progression of non-invasive MGs through 5 years. Data are presented as median and interquartile range. MG mean gradient, NS. not significant; ***p < 0.001

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  Fig. 4. Kaplan–Meier curves for 5-year follow-up regarding Mortality for invasive (A) and non-invasive (B) post-interventional gradients above and below 20 mmHg, as well as regarding major adverse cardiac events (MACE) for invasive (C) and non-invasive (D) post-interventional gradients above and below 20 mmHg. MG mean gradient

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  Fig. 5. Kaplan–Meier curves for 5-year follow-up between patients with severe and moderate post-TAVI patient-prosthesis mismatch (PPM) (indexed aortic valve area < 0.85 cm2/m2) and those without regarding mortality (A) and major adverse cardiac events (MACE) (B)

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  Fig. 6. Relative hazard for mortality at 5-year follow-up for post-TAVI non-invasive mean gradients (left: A, C) and invasive mean gradients (right: B, D) unadjusted, and adjusted for left ventricular ejection fraction and age. LVEF left ventricular ejection fraction, MG mean gradient, TAVI transcatheter aortic valve implantation

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  Fig. 7. Relative hazard for major adverse cardiac events (MACE) at 5-year follow-up for post-TAVI non-invasive mean gradients (left: A, C) and invasive mean gradients (right: B, D) unadjusted, and adjusted for left ventricular ejection fraction and age. LVEF left ventricular ejection fraction, MG mean gradient, TAVI transcatheter aortic valve implantation