Why the study?
Is FSP1 a specific marker for fibroblasts in cardiac remodeling and fibrosis?
Is FSP1 a specific marker for fibroblasts in cardiac remodeling and fibrosis?
FSP1 is not a specific marker for fibroblasts in cardiac remodeling and fibrosis, as it is widely expressed by hematopoietic and vascular cells.
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Caution against relying on FSP1 to identify fibroblasts in cardiac disease; challenges marker specificity and leaves open development of more precise tools.
Kong et al. (2013) studied this question.
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