Why the study?
Does catheter ablation targeting both the endocardial and epicardial aspects of the coronary sinus region improve AF termination in patients with paroxysmal or persistent atrial fibrillation persisting after PV isolation?
Does catheter ablation targeting both the endocardial and epicardial aspects of the coronary sinus region improve AF termination in patients with paroxysmal or persistent atrial fibrillation persisting after PV isolation?
Catheter ablation of the coronary sinus region can terminate atrial fibrillation that persists after pulmonary vein isolation in approximately one-third of patients.
May support adjunctive CS ablation for AF termination post-PVI; leaves open confirmation of benefit and safety in randomized trials.
Catheter ablation targeting both the endocardial and epicardial aspects of the CS region significantly prolongs fibrillatory cycle length and terminates AF persisting after PV isolation in 35% of patients.
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Haı̈ssaguerre et al. (2007) studied this question.
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