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July 22, 2010Obstetrics and Gynecology

Prevention of Preeclampsia and Intrauterine Growth Restriction With Aspirin Started in Early Pregnancy

Emmanuel Bujold Stéphanie Roberge Yves Lacasse Marc Bureau François Audibert Sylvie Marcoux Jean Claude Forest Yves Giguère

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Abstract

Low-dose aspirin initiated in early pregnancy is an efficient method of reducing the incidence of preeclampsia and IUGR.

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Bujold et al. (2010) studied this question.

synapsesocial.com/papers/69d5722775589c71d767e564 https://doi.org/10.1097/aog.0b013e3181e9322a

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1The developmental origins of chronic adult diseaseOriginal Research · 2004 · 791 citations
2Inadequate maternal vascular response to placentation in pregnancies complicated by pre‐eclampsia and by small‐for‐gestational age infantsOriginal Research · 1986 · 1,594 citations
3Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysisDiagnostic Study · 2008 · 722 citations
4Early platelet consumption in pre-eclampsia.Original Research · 1978 · 267 citations
5Flow Cytometric Detection of Activated Platelets in Pregnant Women Prior to the Development of Pre-EclampsiaCohort Study · 1995 · 99 citations

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Prevention of Preeclampsia with Low-Dose Aspirin in Healthy, Nulliparous Pregnant Women1993
Low-Dose Aspirin to Prevent Preeclampsia in Women at High Risk1998
Randomised comparison of uterine artery Doppler and aspirin (100 mg) with placebo in nulliparous women: the Essai Régional Aspirine Mère–Enfant study (Part 2)2003

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