What question did this study set out to answer?

To evaluate the timing of tissue factor (TF) expression during pancreatic neoplastic transformation and assess its relationship with VEGF expression, microvessel density, and venous thromboembolism.

May 15, 2007Clinical Cancer ResearchOpen Access

Tissue Factor Expression, Angiogenesis, and Thrombosis in Pancreatic Cancer

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To evaluate the timing of tissue factor (TF) expression during pancreatic neoplastic transformation and assess its relationship with VEGF expression, microvessel density, and venous thromboembolism.
Assessed tissue factor expression during the early stages of pancreatic neoplastic transformation.
Evaluated correlations between tissue factor levels, vascular endothelial growth factor (VEGF) expression, microvessel density, and clinical venous thromboembolism occurrences.
Tissue factor expression occurs early during neoplastic transformation in pancreatic cancer.
Elevated tissue factor levels associate with increased VEGF expression and higher microvessel density.
Tissue factor expression shows a possible association with clinical venous thromboembolism in pancreatic cancer patients.

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Implication

Observational study reveals tissue factor expression correlates with vascular growth and clotting in pancreatic cancer, indicating its potential role in tumor progression.

Cite This Study

Khorana et al. (2007) studied this question.

synapsesocial.com/papers/69d5724975589c71d767e6cc https://doi.org/10.1158/1078-0432.ccr-06-2351

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Implication

Observational study reveals tissue factor expression correlates with vascular growth and clotting in pancreatic cancer, indicating its potential role in tumor progression.

Tissue Factor Expression, Angiogenesis, and Thrombosis in Pancreatic Cancer

Key Points

Discussion

Implication

Cite This Study

Tissue Factor Expression, Angiogenesis, and Thrombosis in Pancreatic Cancer

Key Points

Discussion

Implication

Cite This Study