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Women with previous GDM and persistent dysglycemia at 5 months postpartum exhibit signs of cardiovascular strain, highlighting a high-risk group that may benefit from early lifestyle or pharmacological interventions.
These findings suggest that women who developed GDM and had persistent dysglycemia at 5 months postpartum have a distinct phenotype which is characterized by increased BMI and signs of cardiovascular strain, including elevated central blood pressure and reduced left ventricular relaxation. These findings suggest that, among women who developed GDM, those with persistent dysglycemia appear to be at increased cardiovascular risk. Further studies are needed to assess whether targeting weight loss with lifestyle or pharmacological interventions can reduce the risk not only for Type-2 diabetes mellitus, but also for later cardiovascular disease.
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Mansukhani et al. (2025) studied this question.
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