Why the study?
Do premature beats and rapid pacing increase spatial inhomogeneity in conduction and initiate reentrant arrhythmias in isolated rabbit left atria?
Population
Isolated superfused left atria of the rabbit
Comparison
Pacing protocols including single early… vs Slow pacing (2 Hz)
Design
Preclinical
Authors
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Phase mapping of conduction inhomogeneity may flag reentry vulnerability in atrial tissue; leaves open translation from rabbit models to clinical substrates.
Do premature beats and rapid pacing increase spatial inhomogeneity in conduction and initiate reentrant arrhythmias in isolated rabbit left atria?
Quantification of spatial inhomogeneities in conduction using phase maps is a useful tool to evaluate the vulnerability of the myocardial substrate for reentrant arrhythmias.
Lammers et al. (1990) studied this question.
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