Observational study reveals elevated serum FGF-21 levels in coronary heart disease, suggesting potential hormone resistance or a compensatory metabolic response.
High levels of FGF-21 are associated with adverse lipid profiles in CHD patients. The paradoxical increase of serum FGF-21 in CHD patients may indicate a compensatory response or resistance to FGF-21.
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Lin et al. (2010) studied this question.
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