Identified a STAT3/miR-21 feedback loop that promotes atrial fibrosis and contributes to atrial fibrillation in a rat model of sterile pericarditis.
Our results have uncovered a novel reciprocal loop between STAT3 and miR-21 that is activated after heart surgery and can contribute to atrial fibrillation.
Huang et al. (Fri,) studied this question.
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