This study provides the first evidence that human epicardial adipose tissue secretes adipo-fibrokines, such as Activin A, which induce fibrosis in the atrial myocardium.
This study provides the first evidence that the secretome from EAT promotes myocardial fibrosis through the secretion of adipo-fibrokines such as Activin A.
Venteclef et al. (2013) studied this question.