The severe cardiorenal syndrome: ‘Guyton revisited’
Population
Patients with combined cardiac failure and chronic renal failure (severe cardiorenal syndrome)
Design
Review
Authors
Discussion
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Member takes
Implication
Theoretical cardiorenal model should not guide therapy; leaves open prospective validation of feedback loops.
Structured PICO
P
Population
Patients with combined cardiac failure and chronic renal failure (severe cardiorenal syndrome)
Provides a theoretical framework for understanding the accelerated morbidity and mortality in severe cardiorenal syndrome through interconnected pathophysiological feedback loops.
Cite This Study
Bongartz et al. (2004) studied this question.