Why the study?
Does nocturnal hypoxic stress activate the invasive ability of monocytes in patients with obstructive sleep apnoea syndrome?
Does nocturnal hypoxic stress activate the invasive ability of monocytes in patients with obstructive sleep apnoea syndrome?
Nocturnal hypoxic stress in OSAS activates monocyte invasiveness, providing a potential mechanistic link to the development of atherosclerosis.
Supports OSAS hypoxia-monocyte link to atherosclerosis; hypothesis-generating, needs prospective trials before practice implications.
These results indicate that OSAS-induced hypoxic stress activates the invasive ability of monocytes, and that the occurrence of this phenomenon during sleep may contribute to the development of atherosclerosis in OSAS.
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Tamaki et al. (2009) studied this question.
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