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January 1, 2015Thrombosis and Haemostasis

Platelets, inflammation and anti-inflammatory effects of antiplatelet drugs in ACS and CAD

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Why the study?

What are the mechanisms by which antiplatelet drugs exert anti-inflammatory effects in patients with ACS and CAD?

Population

Patients with acute coronary syndrome (ACS) and coronary artery disease (CAD)

Design

Review

Authors

KMKarin MüllerMCMadhumita ChatterjeeDRDominik Rath

Discussion

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Overview

May inform antiplatelet choice in ACS/CAD; leaves open whether anti-inflammatory effects alter outcomes.

Structured PICO

What are the mechanisms by which antiplatelet drugs exert anti-inflammatory effects in patients with ACS and CAD?

P
Population
Patients with acute coronary syndrome (ACS) and coronary artery disease (CAD)
I
Intervention
Antiplatelet therapy

This review highlights the dual role of antiplatelet therapy in inhibiting aggregation and modulating chronic inflammation in cardiovascular disease.

Cite This Study

Müller et al. (2015) studied this question.

synapsesocial.com/papers/69d574be6c5a512fd3f50efahttps://doi.org/10.1160/th14-11-0947
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