Key result
Platelet-mediated inflammatory pathways contribute to atherogenesis and operate despite the wide use of platelet-inhibiting drugs, underscoring the need for new targeted therapeutic tools.
Design
Review
Authors
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Does not support practice changes; leaves open whether targeted anti-inflammatory platelet therapies will improve atherosclerotic outcomes.
Highlights the role of platelets as inflammatory mediators in atherosclerosis and the need for novel therapies targeting platelet-mediated inflammation.
Aukrust et al. (2010) conducted a review in Atherosclerosis. Platelet-mediated inflammation was evaluated. Platelet-mediated inflammatory pathways contribute to atherogenesis and operate despite the wide use of platelet-inhibiting drugs, underscoring the need for new targeted therapeutic tools.
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