Why the study?
Does left ventricular loading condition impact the 2D speckle tracking-derived left ventricular dyssynchrony index in nonischemic dilated cardiomyopathy?
Does left ventricular loading condition impact the 2D speckle tracking-derived left ventricular dyssynchrony index in nonischemic dilated cardiomyopathy?
Left ventricular loading conditions significantly impact the 2D speckle tracking-derived left ventricular dyssynchrony index, which should be considered when evaluating patients for cardiac resynchronization therapy.
LV loading may affect dyssynchrony index assessment for CRT; leaves open need for prospective validation in nonischemic cardiomyopathy.
To the best of our knowledge, the present study provides the first evidence of a significant association between LVdys and LV loading status, reflective of a dynamic nature of LVdys. Accordingly, LV loading conditions should be taken into account when echocardiographic LVdys is used for clinical decision-making of selecting candidates for cardiac resynchronization therapy or when it is used as a surrogate marker of prognosis.
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Park et al. (2010) studied this question.
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