Why the study?
To provide guidance, clinical considerations, and a framework for the clinical evaluation and treatment of patients suffering from supine hypertension with orthostatic hypotension.
This review provides a framework for the clinical evaluation and management of patients with supine hypertension and orthostatic hypotension.
May guide management of supine hypertension with orthostatic hypotension; leaves open prospective validation.
This article is intended to provide guidance and clinical considerations for physicians managing patients suffering from supine hypertension with orthostatic hypotension, referred to as "SH-OH". We review the normal physiologic response to orthostasis, focusing on the appropriate changes to autonomic output in this state. Autonomic failure is discussed with a generalized overview of the disease and examination of specific syndromes that help shed light on the pathophysiology of SH-OH. The goal of this review is to provide a better framework for clinical evaluation of these patients, review treatment options, and ultimately work toward achieving a better quality of life for patients afflicted with this disease.
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Ahmed et al. (2019) studied this question.
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