Why the study?
Does left atrial longitudinal strain by speckle tracking echocardiography improve the estimation of invasively obtained LV filling pressures compared to E/Em ratio in patients with advanced systolic heart failure?
Does left atrial longitudinal strain by speckle tracking echocardiography improve the estimation of invasively obtained LV filling pressures compared to E/Em ratio in patients with advanced systolic heart failure?
Left atrial longitudinal strain by speckle tracking echocardiography provides a more accurate non-invasive estimation of LV filling pressures than the traditional E/Em ratio in patients with advanced systolic heart failure.
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LA strain by STE may better estimate filling pressures than E/Em in advanced HF; hypothesis-generating, needs prospective validation.
In a group of patients with advanced systolic heart failure, E/Em ratio correlated poorly with invasively obtained LV filling pressures. However, LA longitudinal deformation analysis by STE correlated well with PCWP, providing a better estimation of LV filling pressures in this particular clinical setting.
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Cameli et al. (2010) studied this question.
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