Why the study?
Does left atrial strain (global PALS) correlate better than E/E' ratio with invasively measured LVEDP across different strata of left ventricular ejection fraction?
Population
80 stable patients with sinus rhythm undergoing cardiac catheterization, stratified into four groups of 20…
Comparison
Measurement of peak atrial longitudinal strain… vs Invasive measurement of left ventricular…
Design
Cross-sectional
Authors
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PALS may better estimate LVEDP than E/E' across LVEF strata; hypothesis-generating and requires prospective validation before clinical adoption.
Does left atrial strain (global PALS) correlate better than E/E' ratio with invasively measured LVEDP across different strata of left ventricular ejection fraction?
Global peak atrial longitudinal strain provides a more reliable non-invasive estimation of left ventricular filling pressures than the E/E' ratio, particularly in patients with moderately or severely reduced ejection fraction.
Cameli et al. (2015) studied this question.
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