Why the study?
The relationship between an index combining LV diastolic function parameters with LA strain and diastolic function in patients with preserved ejection fraction remained to be explored.
Does the E/LASr ratio accurately predict elevated left ventricular filling pressures in patients with preserved LVEF?
Population
388 patients with LVEF >= 50%
Comparison
Test group undergoing left heart catheterization vs validation group
Design
Prospective cohort study
Follow-up
one year
Authors
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May support non-invasive estimation of elevated filling pressures in preserved LVEF; hypothesis-generating and requires prospective validation before practice change.
Does the E/LASr ratio accurately predict elevated left ventricular filling pressures in patients with preserved LVEF?
The E/LASr ratio is a highly accurate, non-invasive echocardiographic index for assessing elevated left ventricular filling pressures and diagnosing HFpEF in patients with preserved ejection fraction.
Zhou et al. (2021) studied this question.