Children with severe Parvovirus B19 myocarditis can achieve myocardial recovery if supported through the acute phase with mechanical circulatory support, rarely requiring acute transplantation.
High-risk features predict poor outcomes in pediatric fulminant myocarditis; leaves open whether mechanical support improves survival in prospective trials.
PVB19 can cause a devastating myocarditis in children. Children with fulminant myocarditis, ST segment changes or a short prodrome have the worst outcome. Transplantation may be considered, but is rarely required in the acute period if mechanical circulatory support is utilised. If the initial presentation is survived, recovery of the myocardium can occur even in those who had fulminant myocarditis.
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Vigneswaran et al. (2015) studied this question.
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