Why the study?
Mechanical prosthetic tricuspid valve thrombosis is life-threatening, and evidence guiding management is limited, particularly in poor surgical candidates or after failed thrombolysis.
Does percutaneous mechanical mobilization improve valve function in a patient with a thrombosed mechanical tricuspid valve after failed thrombolysis?
Does percutaneous mechanical mobilization improve valve function in a patient with a thrombosed mechanical tricuspid valve after failed thrombolysis?
Percutaneous mechanical mobilization using an electrophysiology catheter and thrombus aspiration may serve as a feasible bailout strategy for mechanical tricuspid valve thrombosis when surgery and thrombolysis fail.
May provide percutaneous bailout for mechanical tricuspid valve thrombosis after failed thrombolysis; hypothesis-generating pending larger studies.
Mechanical prosthetic tricuspid valve thrombosis is a rare but potentially life-threatening condition. Evidence guiding management is limited, particularly in patients who are poor surgical candidates or who fail thrombolytic therapy. We report an 83-year-old woman with a mechanical tricuspid valve who presented with progressive right-sided heart failure due to obstructive valve thrombosis. After failure of anticoagulation and low-dose thrombolytic therapy, a percutaneous catheter-based approach was performed. Using a steerable sheath and electrophysiology catheter, mechanical mobilization of the stuck leaflet was achieved, followed by thrombus aspiration. Leaflet mobility was restored, and transvalvular gradients significantly improved without complications. In carefully selected patients with mechanical tricuspid valve thrombosis who are not candidates for surgery and fail thrombolytic therapy, percutaneous mechanical mobilization may represent a feasible and effective bailout strategy.
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Yavuz et al. (2026) studied this question.
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