Does daily sitting time ≥8 hours increase the risk of heart attack and cardiovascular mortality compared to sitting <4 hours?
Prolonged daily sitting (≥8 hours) is associated with an increased risk of heart attack and cardiovascular mortality, a relationship potentially mediated by serum osmolality.
Daily sitting time was significantly associated with the risk of heart attack and cardiovascular mortality; participants sitting ≥8 hours had a higher incidence than those sitting <4 hours. Serum osmolality plays a key mediating role in the impact of sitting time on heart attack development.
Chen et al. (Tue,) studied this question.