Randomized trial demonstrates lower morbidity and costs with laparoscopic cholecystectomy within 24 hours in acute cholecystitis, indicating immediate surgery should be the preferred treatment.
In this large, randomized trial, laparoscopic cholecystectomy within 24 hours of hospital admission was shown to be superior to the conservative approach concerning morbidity and costs. Therefore, we believe that immediate laparoscopic cholecystectomy should become therapy of choice for acute cholecystitis in operable patients. (NCT00447304).
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Gutt et al. (2013) studied this question.
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