What question did this study set out to answer?

To evaluate how the timing of laparoscopic cholecystectomy relative to hospital admission affects clinical outcomes in patients presenting with acute cholecystitis.

August 4, 2011Annals of Surgery

Population-Based Analysis of 4113 Patients With Acute Cholecystitis

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Authors

VBVanessa BanzUniversity of Bern TGThomas GsponerPsychiatriezentrum Münsingen DCDaniel CandinasUniversité Paris-Sud

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Implication

Cohort study reveals increased complications and conversion rates with delayed surgery in acute cholecystitis, suggesting intervention within 48 hours.

Key Points

To evaluate how the timing of laparoscopic cholecystectomy relative to hospital admission affects clinical outcomes in patients presenting with acute cholecystitis.
Analyzed prospective registry data from the Swiss Association of Laparoscopic and Thoracoscopic Surgery for emergency laparoscopic cholecystectomies between 1995 and 2006 (N=4113).
Stratified patients by timing of surgery following admission: day 0, day 1, day 2, day 3, days 4–5, and day ≥6.
Utilized linear and generalized linear regression models to evaluate the relationship between surgical delay and conversion to open surgery, intra- and postoperative complications, reoperations, and hospital stay.
Delaying surgery significantly increased open conversion rates from 11.9% on admission day (d0) to 27.9% on day ≥6 (P < 0.001).
Surgical postoperative complications rose from 5.7% at d0 to 13% at d ≥6 (P < 0.001), while reoperation rates increased from 0.9% to 3% (P = 0.007).
Postoperative hospital length of stay grew significantly longer as the delay before surgery increased (P < 0.001).

Cite This Study

Banz et al. (2011) studied this question.

synapsesocial.com/papers/6a73e9356acfb9d2a78decf7 https://doi.org/10.1097/sla.0b013e318228d31c

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Implication

Cohort study reveals increased complications and conversion rates with delayed surgery in acute cholecystitis, suggesting intervention within 48 hours.

Population-Based Analysis of 4113 Patients With Acute Cholecystitis

Discussion

Member takes

Implication

Key Points

Cite This Study

Population-Based Analysis of 4113 Patients With Acute Cholecystitis

Discussion

Member takes

Implication

Key Points

Cite This Study

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