What question did this study set out to answer?

To systematically review and analyze the impact of hidradenitis suppurativa signs and symptoms, including pain, pruritus, malodour, and suppuration, on patient quality of life.

June 22, 2021International Journal of Environmental Research and Public HealthOpen Access

The Burden of Hidradenitis Suppurativa Signs and Symptoms in Quality of Life: Systematic Review and Meta-Analysis

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Authors

TMTrinidad Montero‐VílchezUniversidad de Granada PDPablo Díaz‐CalvilloInstituto de Investigación Biosanitaria de Granada JRJuan-Ángel Rodríguez-PozoHospital Universitario Virgen de las Nieves

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Implication

Systematic review and meta-analysis finds that symptom severity diminishes quality of life in hidradenitis suppurativa, highlighting the need for routine multi-symptom clinical evaluation.

Key Points

To systematically review and analyze the impact of hidradenitis suppurativa signs and symptoms, including pain, pruritus, malodour, and suppuration, on patient quality of life.
A systematic review and meta-analysis was conducted following PRISMA guidelines, identifying 17 eligible studies representing N = 4,929 participants with mild to moderate disease.
Included cohorts had a mean age of 36.28 years, a predominance of female participants, a mean disease duration of 13.69 years, and an average BMI in the overweight range.
Greater intensity of signs and symptoms correlated with poorer general quality of life, as well as specific impairments in sleep, anxiety, depression, and sexual distress.
The Dermatology Life Quality Index (DLQI) was the primary metric used in 52.9% (9/17) of studies, yielding a pooled mean score of 10.70 (SD 2.16).
Symptom severity was most frequently measured via numerical rating scales (NRS), demonstrating a mean score of 3.99 for pain and 4.99 for pruritus.

Cite This Study

Montero‐Vílchez et al. (2021) studied this question.

synapsesocial.com/papers/69d6a8b8f174babf6cab30e4 https://doi.org/10.3390/ijerph18136709

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Implication

Systematic review and meta-analysis finds that symptom severity diminishes quality of life in hidradenitis suppurativa, highlighting the need for routine multi-symptom clinical evaluation.

The Burden of Hidradenitis Suppurativa Signs and Symptoms in Quality of Life: Systematic Review and Meta-Analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

The Burden of Hidradenitis Suppurativa Signs and Symptoms in Quality of Life: Systematic Review and Meta-Analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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