What question did this study set out to answer?

To provide a comprehensive overview of the physiological functions, molecular cargo, and homeostatic roles of extracellular vesicles across cell systems, organs, and diverse biological kingdoms.

January 1, 2015Journal of Extracellular VesiclesOpen Access

Biological properties of extracellular vesicles and their physiological functions

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Authors

MYMarı́a Yáñez-Mó PSPia Siljander ZAZoraida Andreu

Discussion

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Overview

Comprehensive review reveals the physiological roles of extracellular vesicles across diverse organisms, highlighting their conserved function in intercellular communication and homeostasis.

Key Points

To provide a comprehensive overview of the physiological functions, molecular cargo, and homeostatic roles of extracellular vesicles across cell systems, organs, and diverse biological kingdoms.
Synthesized international evidence via a crowdsourced collaboration of academic, clinical, and industrial experts across 27 European countries, the United States, and Australia.
Evaluated extracellular vesicle molecular components—including proteins, lipids, and nucleic acids—across mammalian tissues, biofluids, bacteria, lower eukaryotes, and plants.
Extracellular vesicles act as universal vehicles of intercellular communication across prokaryotes and eukaryotes by transferring bioactive lipids, proteins, and nucleic acids.
Beyond their recognized involvement in pathological states such as cancer and autoimmune disorders, extracellular vesicles fundamentally regulate baseline organ physiology and systemic homeostasis.

Cite This Study

Yáñez-Mó et al. (2015) studied this question.

synapsesocial.com/papers/69d6c511639f29d8dcab311c https://doi.org/10.3402/jev.v4.27066

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January 1, 2015Journal of Extracellular VesiclesOpen Access

Biological properties of extracellular vesicles and their physiological functions

View Full Paper

Ask AI

Bookmark

Authors

MYMarı́a Yáñez-Mó PSPia Siljander ZAZoraida Andreu

Discussion

Member takes

Overview

Comprehensive review reveals the physiological roles of extracellular vesicles across diverse organisms, highlighting their conserved function in intercellular communication and homeostasis.

Key Points

To provide a comprehensive overview of the physiological functions, molecular cargo, and homeostatic roles of extracellular vesicles across cell systems, organs, and diverse biological kingdoms.
Synthesized international evidence via a crowdsourced collaboration of academic, clinical, and industrial experts across 27 European countries, the United States, and Australia.
Evaluated extracellular vesicle molecular components—including proteins, lipids, and nucleic acids—across mammalian tissues, biofluids, bacteria, lower eukaryotes, and plants.
Extracellular vesicles act as universal vehicles of intercellular communication across prokaryotes and eukaryotes by transferring bioactive lipids, proteins, and nucleic acids.
Beyond their recognized involvement in pathological states such as cancer and autoimmune disorders, extracellular vesicles fundamentally regulate baseline organ physiology and systemic homeostasis.

Cite This Study

Yáñez-Mó et al. (2015) studied this question.

synapsesocial.com/papers/69d6c511639f29d8dcab311c https://doi.org/10.3402/jev.v4.27066

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