What question did this study set out to answer?

To present ESPript and ENDscript, integrated web-based programs designed to extract, analyze, and render protein sequence alignments adorned with 3D structural data.

June 25, 2003Nucleic Acids ResearchOpen Access

ESPript/ENDscript: extracting and rendering sequence and 3D information from atomic structures of proteins

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Authors

PGPatrice GouetUniversité Claude Bernard Lyon 1

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Implication

Bioinformatics report demonstrates automated rendering of protein alignments and 3D atomic structures, highlighting streamlined visualization of sequence conservation.

Key Points

To present ESPript and ENDscript, integrated web-based programs designed to extract, analyze, and render protein sequence alignments adorned with 3D structural data.
Interfaced the ESPript rendering tool with external bioinformatics services, including ProDom, PredictProtein, and NPS@.
Developed the ENDscript server using sequence tools (BLAST, Clustal, PHYLODENDRON) and coordinate processing programs (DSSP, CNS, MOLSCRIPT) to process single Protein Data Bank queries.
Coupled structural superposition using PROFIT with final rendering using BOBSCRIPT to map sequence and structural conservation directly onto the C-alpha trace.
Automated the production of publication-quality multiple sequence alignment figures decorated with secondary structure elements derived from known 3D structures.
Streamlined the comparative mapping of sequence conservation and 3D structural overlaps using an automated, single-identifier web workflow.

Cite This Study

Patrice Gouet (2003) studied this question.

synapsesocial.com/papers/69d6cfacfca0359822aa89ed https://doi.org/10.1093/nar/gkg556

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Implication

Bioinformatics report demonstrates automated rendering of protein alignments and 3D atomic structures, highlighting streamlined visualization of sequence conservation.

ESPript/ENDscript: extracting and rendering sequence and 3D information from atomic structures of proteins

Discussion

Member takes

Implication

Key Points

Cite This Study

ESPript/ENDscript: extracting and rendering sequence and 3D information from atomic structures of proteins

Discussion

Member takes

Implication

Key Points

Cite This Study

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