Shift of the TSH reference range with improved iodine supply in Northeast Germany

This is the authors' abstract. We don't add key points for this paper.

We demonstrate a shift toward the right of the TSH reference range in comparison with data from the same study region 10 years earlier, which is likely due to the improved iodine supply of the study region. Our study indicates that TSH reference limits are dependent on past and current iodine supply of populations.