The Corrected TIMI Frame Count (CTFC) provides a standardized, objective, and quantitative measure of coronary flow for comparing angiographic endpoints.
May standardize angiographic flow assessment in practice; leaves open validation as a primary trial endpoint.
The CTFC is a simple, reproducible, objective and quantitative index of coronary flow that allows standardization of TIMI flow grades and facilitates comparisons of angiographic end points between trials. Disordered resistance vessel function may account in part for reductions in flow in the early hours after thrombolysis.
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Gibson et al. (1996) studied this question.
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