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Demonstrates that an AI denoising algorithm maintains PET image quality at half signal in recurrent prostate cancer, suggesting caution during longitudinal quantitative monitoring.
We show that the SubtlePET® can be used for ⁶⁸ Ga-PSMA scans using half the signal with similar image quality to Q.Clear series and superior quality to VPFX series. However, it significantly modifies quantitative measurements and should not be used for comparative examinations if standard algorithm is applied during follow-up.
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Margail et al. (2023) studied this question.
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