Why the study?
Does gastric bypass surgery reduce the incidence of heart failure compared to intensive lifestyle modification?
Does gastric bypass surgery reduce the incidence of heart failure compared to intensive lifestyle modification?
Gastric bypass surgery is associated with a substantially lower incidence of heart failure compared to intensive lifestyle modification, demonstrating a graded benefit with increasing weight loss.
Supports hypothesis of weight loss benefit for HF prevention; should not yet change practice pending RCTs.
Gastric bypass surgery was associated with approximately one half the incidence of heart failure compared with intensive lifestyle modification in this study of 2 large nationwide registries. We also observed a graded association between increasing weight loss and decreasing risk of heart failure.
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Sundström et al. (2017) studied this question.
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