Why the study?
Is restrictive intraoperative vascular filling < 5ml/kg/h associated with postoperative acute kidney injury in bladder cancer patients undergoing radical cystectomy?
Is restrictive intraoperative vascular filling < 5ml/kg/h associated with postoperative acute kidney injury in bladder cancer patients undergoing radical cystectomy?
Restrictive intraoperative fluid management (< 5ml/kg/h) during radical cystectomy is associated with increased risk of postoperative AKI and subsequent CKD.
Answers are grounded in this paper and cite their sources.
May raise postoperative AKI risk after cystectomy; leaves open confirmation in prospective trials before practice change.
A restrictive intraoperative vascular filling < 5ml/kg/h was strongly and independently associated with the occurrence of postoperative AKI after RC in cancer bladder patients. In this context, postoperative AKI was strongly associated with the occurrence or worsening of CKD within the 2 years following RC. A personalized perioperative fluid management strategy needs to be evaluated in these high-risk patients.
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Marques et al. (2024) studied this question.
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