April 16, 2013European Heart Journal191 citationsOpen Access
View Full PaperLack of evidence of increased mortality among patients with atrial fibrillation taking digoxin: findings from post hoc propensity-matched analysis of the AFFIRM trial
Structured PICO
Does digoxin as baseline initial therapy increase mortality or hospitalization in patients with paroxysmal and persistent atrial fibrillation?
P
Population
Patients with paroxysmal and persistent atrial fibrillation (from the AFFIRM trial)
I
Intervention
Digoxin as baseline initial therapy
O
Outcome
Mortality or hospitalizationhard clinical
In a post hoc analysis of the AFFIRM trial, baseline digoxin therapy was not associated with increased mortality or hospitalization in patients with atrial fibrillation.
Abstract
In patients with paroxysmal and persistent AF, we found no evidence of increased mortality or hospitalization in those taking digoxin as baseline initial therapy.