Do antidiabetic agents affect mortality and harm in patients with diabetes and heart failure?
Metformin appears to be the only safe antidiabetic agent in patients with concurrent diabetes and heart failure, potentially reducing all-cause mortality.
Metformin was the only antidiabetic agent not associated with harm in patients with heart failure and diabetes. It was associated with reduced all cause mortality in two of the three studies.
Eurich et al. (Thu,) studied this question.