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January 29, 2025Cardiovascular Diabetology125 citationsOpen Access

The triglyceride–glucose index and its obesity-related derivatives as predictors of all-cause and cardiovascular mortality in hypertensive patients: insights from NHANES data with machine learning analysis

CLChenyang LiZZZixi ZhangXLXiao-Qin Luo

Structured PICO

Do the triglyceride-glucose index and its obesity-related derivatives predict all-cause and cardiovascular mortality in hypertensive patients?

P
Population
Hypertensive patients from NHANES data
I
Intervention
Triglyceride-glucose (TyG) index and its obesity-related derivatives
O
Outcome
All-cause and cardiovascular mortalityhard clinical

The TyG index and its obesity-related derivatives enhance risk stratification for all-cause and cardiovascular mortality in hypertensive patients.

Limitations

  • Needs validation in external hypertensive cohorts

Abstract

The TyG index and its derivatives are significant predictors of mortality in hypertensive patients. Their inclusion in predictive models enhances risk stratification and may aid in the early identification of high-risk individuals in this population. Further studies are needed to validate these findings in external hypertensive cohorts.

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Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/69d73ad2aa68b335b4f308e2https://doi.org/10.1186/s12933-025-02591-1
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