What are the long-term outcomes and prognostic factors in ARVD/C patients and their family members?
Long-term outcomes in ARVD/C are favorable when diagnosed and treated, with ICDs playing a key role in index patients and genetic/symptom screening important for family members.
Long-term outcome was favorable in diagnosed and treated ARVD/C index-patients and family members. Outcome in index-patients was modulated by implantable cardioverter-defibrillator implantation, but not by mutation status and familial background of disease. One third of family members developed ARVD/C. Outcome in family members was determined by symptoms at first evaluation and mutations.
Groeneweg et al. (Sun,) studied this question.