Why the study?
Does exercise training improve NO-mediated microvascular vasodilator function in older sedentary subjects?
Population
Young, older sedentary, and older fit subjects
Comparison
Exercise training for 12 and 24 weeks vs Baseline and older fit/young subjects
Design
Cohort
Follow-up
24 weeks
Authors
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May support exercise to preserve microvascular NO function in aging; hypothesis-generating for anti-atherogenic effects, needs RCTs.
Does exercise training improve NO-mediated microvascular vasodilator function in older sedentary subjects?
Maintaining high fitness or undertaking exercise training prevents age-related decline in NO-mediated microvascular vasodilator function, which may confer anti-atherogenic benefits.
Black et al. (2008) studied this question.
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