Why the study?
Does laser Doppler imaging of cutaneous microvascular responses to reactive hyperaemia provide superior diagnostic accuracy for coronary artery disease compared to brachial artery flow-mediated dilation?
Population
48 subjects, comprising 24 patients with coronary artery disease (CAD) and 24 healthy controls.
Comparison
Laser Doppler imaging to assess cutaneous… vs Brachial artery flow-mediated dilation (FMD).
Design
Case-control
Authors
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May support laser Doppler time-to-peak for CAD detection given high specificity; extends microvascular data but leaves open superiority to flow-mediated dilation.
Does laser Doppler imaging of cutaneous microvascular responses to reactive hyperaemia provide superior diagnostic accuracy for coronary artery disease compared to brachial artery flow-mediated dilation?
Laser Doppler-derived time to peak response to reactive hyperaemia offers superior specificity for diagnosing coronary artery disease compared to traditional brachial artery flow-mediated dilation.
SHAMIM-UZZAMAN et al. (2002) studied this question.
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