Answers are grounded in this paper and cite their sources.
A new method for isolation of high molecular weight DNA from eukaryotes is presented. This procedure allows preparation of DNA from a variety of tissues such as calf thymus or human placenta and from cells which were more difficult to lyse until now (e.g. Crypthecodinium cuhnii, a dinoflagellate). The DNA obtained in such a way has an average molecular weight of about 200 X 10(6) d and contains very few, if any, single strand breaks.
No takes yet. Share an insight, caveat, or question.
Blin et al. (1976) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: