Why the study?
Does intra-operative dexmedetomidine reduce postoperative pain and improve recovery in patients undergoing colorectal surgery?
Population
100 patients undergoing open or conventional laparoscopic colorectal surgery
Comparison
Intra-operative loading dose of dexmedetomidine… vs Bolus and infusion of saline 0.9% of equivalent…
Design
RCT, randomised, double-blind
Follow-up
48 hours postoperatively
Authors
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Reduces resting pain after colorectal surgery without morphine-sparing or recovery benefits; extends sparse RCT evidence but leaves clinical adoption open.
Does intra-operative dexmedetomidine reduce postoperative pain and improve recovery in patients undergoing colorectal surgery?
Intra-operative dexmedetomidine reduces resting pain scores after colorectal surgery but does not have a morphine-sparing effect or improve recovery times.
Cheung et al. (2014) studied this question.
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