What question did this study set out to answer?

To quantify hepatic triglyceride content and examine ethnic and sex disparities in the prevalence of hepatic steatosis within a large, diverse urban population.

November 24, 2004Hepatology

Prevalence of Hepatic Steatosis in An Urban Population in the United States: Impact of Ethnicity

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Authors

JBJeffrey D. BrowningRoyal Berkshire Hospital LSLidia S. SzczepaniakVisionQuest Biomedical (United States)RDRobert L. DobbinsIndivior (United States)

Discussion

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Implication

Cross-sectional study reveals marked ethnic differences in hepatic steatosis prevalence across an urban population, highlighting distinct susceptibilities to progressive liver disease.

Key Points

To quantify hepatic triglyceride content and examine ethnic and sex disparities in the prevalence of hepatic steatosis within a large, diverse urban population.
Conducted a population-based cross-sectional assessment of N=2,287 individuals (32.1% White, 48.3% Black, and 17.5% Hispanic).
Measured hepatic triglyceride content using proton magnetic resonance spectroscopy and evaluated metabolic parameters alongside serum alanine aminotransferase.
Hepatic steatosis occurred in roughly one-third of the population, and 79% of affected individuals exhibited normal serum alanine aminotransferase levels.
Steatosis frequency varied significantly by ethnicity (45% in Hispanics, 33% in Whites, and 24% in Blacks) and differed by sex in Whites (42% in men vs. 24% in women).
Higher rates in Hispanics tracked with elevated obesity and insulin resistance, whereas lower rates in Blacks remained unexplained by body mass index, insulin resistance, alcohol intake, or medication use.

Cite This Study

Browning et al. (2004) studied this question.

synapsesocial.com/papers/69d76df7aa68b335b4f316de https://doi.org/10.1002/hep.20466

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November 24, 2004Hepatology

Prevalence of Hepatic Steatosis in An Urban Population in the United States: Impact of Ethnicity

View Full Paper

Ask AI

Bookmark

Authors

JBJeffrey D. BrowningRoyal Berkshire Hospital LSLidia S. SzczepaniakVisionQuest Biomedical (United States)RDRobert L. DobbinsIndivior (United States)

Discussion

Member takes

Implication

Cross-sectional study reveals marked ethnic differences in hepatic steatosis prevalence across an urban population, highlighting distinct susceptibilities to progressive liver disease.

Key Points

To quantify hepatic triglyceride content and examine ethnic and sex disparities in the prevalence of hepatic steatosis within a large, diverse urban population.
Conducted a population-based cross-sectional assessment of N=2,287 individuals (32.1% White, 48.3% Black, and 17.5% Hispanic).
Measured hepatic triglyceride content using proton magnetic resonance spectroscopy and evaluated metabolic parameters alongside serum alanine aminotransferase.
Hepatic steatosis occurred in roughly one-third of the population, and 79% of affected individuals exhibited normal serum alanine aminotransferase levels.
Steatosis frequency varied significantly by ethnicity (45% in Hispanics, 33% in Whites, and 24% in Blacks) and differed by sex in Whites (42% in men vs. 24% in women).
Higher rates in Hispanics tracked with elevated obesity and insulin resistance, whereas lower rates in Blacks remained unexplained by body mass index, insulin resistance, alcohol intake, or medication use.

Cite This Study

Browning et al. (2004) studied this question.

synapsesocial.com/papers/69d76df7aa68b335b4f316de https://doi.org/10.1002/hep.20466

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