Population
Adolescents and young adults with osteosarcoma
Design
Review
Authors
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No survival gains in osteosarcoma over 30 years; leaves open biology-driven systemic therapies for prospective trials.
While limb-salvage techniques have improved, overall survival for osteosarcoma has not significantly increased in 30 years, underscoring the need for novel treatment approaches based on tumor biology.
Bielack et al. (2016) studied this question.
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