Why the study?
Does ginsenoside Rg1 improve myocardial remodeling and pulmonary hemodynamics in an animal model of CTEPH?
Does ginsenoside Rg1 improve myocardial remodeling and pulmonary hemodynamics in an animal model of CTEPH?
Ginsenoside Rg1 demonstrates beneficial effects on myocardial remodeling and pulmonary hemodynamics in a CTEPH animal model, possibly mediated by MMP-2 and MMP-9 upregulation.
Hypothesis-generating in CTEPH model; leaves open human translation pending prospective trials.
Our animal study showed that ginsenoside Rg1 positively affects myocardial remodeling and pulmonary hemodynamics in CTEPH. Upregulation of the expression of MMP-2 and MMP-9 could explain the beneficial effects of ginsenoside Rg1 in CTEPH.
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Li et al. (2013) studied this question.
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