Why the study?
Is alveolar-capillary membrane diffusing capacity a useful marker for alveolar-capillary barrier damage and functional status in chronic heart failure?
Is alveolar-capillary membrane diffusing capacity a useful marker for alveolar-capillary barrier damage and functional status in chronic heart failure?
Alveolar-capillary membrane diffusing capacity (DM) may serve as a useful marker for alveolar-capillary barrier damage due to elevated pulmonary capillary pressure in chronic heart failure.
DM may mark alveolar-capillary barrier damage and functional status in CHF; hypothesis-generating and should not yet change practice.
Reduced alveolar-capillary membrane diffusing capacity is the major component of impaired pulmonary gas transfer in CHF, correlating with maximal exercise capacity and functional status. DM may be a useful marker for the alveolar-capillary barrier damage induced by raised pulmonary capillary pressure.
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Puri et al. (1995) studied this question.
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