Key result
Greater severity of mitral valve disease was significantly associated with reductions in forced expiratory volume, vital capacity, and TLCO, and an increase in residual volume.
Why the study?
Does the severity of mitral valve disease correlate with abnormalities in routine lung function tests in non-smoking patients?
Population
26 non-smoking patients with mitral valve disease undergoing cardiac catheterisation
Design
Cross-sectional
Authors
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Supports accounting for mitral valve severity when interpreting restrictive PFT patterns in non-smokers; leaves open clinical utility and causal mechanisms.
Observational (n=26)
Does the severity of mitral valve disease correlate with abnormalities in routine lung function tests in non-smoking patients?
The severity of mitral valve disease in non-smokers correlates significantly with restrictive and diffusion abnormalities on routine lung function tests, which can be distinguished from primary airway disease by a normal forced expiratory ratio.
Rhodes et al. (1982) conducted an observational in Mitral valve disease (n=26). Severity of mitral valve disease was evaluated on Lung volumes and carbon monoxide transfer factor (TLCO). Greater severity of mitral valve disease was significantly associated with reductions in forced expiratory volume, vital capacity, and TLCO, and an increase in residual volume.
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