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November 16, 2004JNCI Journal of the National Cancer InstituteOpen Access

Reactivation of Latent Epstein-Barr Virus by Methotrexate: A Potential Contributor to Methotrexate-Associated Lymphomas

Wen-hai Feng Jeffrey I. Cohen Susan M. Fischer L. Li M. Sneller Raphaela Goldbach‐Mansky N. Raab-Traub Henri‐Jacques Delecluse S. C. Kenney

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Abstract

MTX may promote EBV-positive lymphomas in rheumatoid arthritis and polymyositis patients by its immunosuppressive properties as well as by reactivating latent EBV.

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Feng et al. (2004) studied this question.

synapsesocial.com/papers/69d788415f9a1dad5349069d https://doi.org/10.1093/jnci/djh313

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