February 1, 2017Catheterization and Cardiovascular Interventions138 citations

Device‐associated thrombus formation after left atrial appendage occlusion: A systematic review of events reported with the Watchman, the Amplatzer Cardiac Plug and the Amulet

MLMathieu LempereurInserm AAAdel AminianInterventional / Structural Cardiology XFXavier FreixaInterventional Cardiology

Structured PICO

What are the characteristics, clinical outcomes, and management of device-associated thrombus formation after left atrial appendage occlusion?

Population

Patients undergoing percutaneous left atrial appendage occlusion (LAAO) with Watchman, Amplatzer Cardiac Plug, or Amulet devices

Intervention

Percutaneous left atrial appendage occlusion (LAAO) with Watchman, Amplatzer Cardiac Plug, or Amulet devices

Outcome

Device-associated thrombus (DAT) formation and associated neurological complicationssafety

Device-associated thrombus after LAAO is an infrequent, early complication with low neurological risk that can be effectively managed with anticoagulation.

Abstract

DAT is an infrequent complication of percutaneous LAAO. It occurs mainly early after the procedure and is associated with a low rate of neurological complications. In the majority of cases, diagnosis is made during follow-up imaging with TEE. Anticoagulation treatment seems to be safe and highly effective. Further studies are needed to evaluate the optimal management of DAT. © 2017 Wiley Periodicals, Inc.

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